Female Infertility Causes
The most common female infertility cause is an ovulation disorder. Other causes of female infertility include blocked fallopian tubes, which can occur when a woman has had pelvic inflammatory disease or endometriosis (a sometimes painful condition causing adhesions and cysts). Congenital anomalies (birth defects) involving the structure of the uterus and uterine fibroids are associated with repeated miscarriages
In females, possible factors implicated include an active sexual life starting at a very young age, an increased number of pregnancy terminations and multiple sexual partners (sexually transfered diseases as chlamydia etc). Most importantly, concern has been expressed about the decision some women have made in postponing having a baby, giving reasons such as education, career advancement and not yet finding the “right” man until late 30’s or even early 40’s.
Ovulation disorders account for infertility in 25 percent of infertile couples. These can be caused by flaws in the regulation of reproductive hormones by the hypothalamus or the pituitary gland, or by problems in the ovary itself. You have an ovulation disorder if you ovulate infrequently or not at all.
Abnormal FSH and LH secretion
The two hormones responsible for stimulating ovulation each month – follicle-stimulating hormone (FSH) and luteinizing hormone (LH) – are produced by the pituitary gland in a specific pattern during the menstrual cycle. Excess physical or emotional stress or a very high or very low body weight can disrupt this pattern and affect ovulation. The main sign of this problem is irregular or absent periods. Much less commonly, specific diseases of the pituitary, usually associated with other hormone deficiencies, may be the cause.
Polycystic ovary syndrome (PCOS)
In PCOS, complex changes occur in the hypothalamus, pituitary and ovary, resulting in overproduction of male hormones (androgens), which affects ovulation. PCOS can also be associated with insulin resistance and obesity.
Luteal phase defect
Luteal phase defect happens when the ovary doesn’t produce enough of the hormone progesterone after ovulation. Progesterone is vital in preparing the uterine lining for a fertilized egg.